With countless sugar alternatives flooding the market, it can be dizzying to know which sweeteners support your health and which ones might be working against you. Today we're examining sucralose—better known by its brand name Splenda—and why many health professionals are recommending you skip this artificial option altogether. What Exactly Is Sucralose? Sucralose is an artificial sweetener developed in the 1970s through a fascinating but concerning process: sugar chemically